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What autoimmune disease causes hives? Autoimmune Urticaria (Hives) Mast cells are the cells in the skin and mucous membranes that contain histamine. Release of histamine causes the allergic symptoms of hives and angioedema (swelling of large areas of the body). Rheumatoid arthritis is a good example of an autoimmune disease.
Can u die from hives? Hives usually cause itching, but may also burn or sting. It generally lasts longer than hives, but the swelling usually goes away in less than 24 hours. Rarely, angioedema of the throat, tongue, or lungs can block the airways, causing difficulty breathing. This may become life threatening.
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